"Riboxin": indications, reviews, analogues and price
What is Riboxin prescribed for? Indications for use of this tool, its side effects and contraindications will be described in detail in this article. We will also tell you about the forms of release of the mentioned agent, we will present its pharmacological characteristics, dosage, and so on.
Forms of release of the drug and their composition
What are the forms of the drug Riboxin? Indications for use of this drug may be different. In this regard, pharmaceutical companies began to produce several forms of the drug. Consider them in more detail.
- Tablets "Riboxin".Indications for use and dosage of this form will be described in detail later. This medicine is coated and contains an active substance called inosine (0.2 g per tablet). This drug goes on sale in carton packs of 10, 20, 30, 40, or 50 pieces.
- Solution for injection "Riboxin" (ampoules).Indications for use include diseases requiring the immediate introduction of the drug into the bloodstream. This medicine also includes the active substance inosine (in the amount of 20 mg). In addition, it also contains auxiliary elements such as sodium hydroxide, propylene glycol, water for injection and anhydrous sodium sulfite. In the sale of the drug comes in 10 ampoules or 5 ml. As a rule, there are 10 ampoules in a package.
- Capsules "Riboxin".This tool contains the active substance inosine in the amount of 200 mg. In the carton can be 50 or 10 pieces.
Pharmacological properties of the drug
In what cases is the doctor prescribed the medicine Riboxin? Indications for use of this tool are able to give an exhaustive answer to the question posed.
This drug is a metabolic agent, which is very often used for complex treatment of coronary heart disease.
As mentioned above, the active substance of the drug "Riboxin" is inosine. It is he, getting into the human body, promotes the regulation of all metabolic processes.Due to its composition, the said drug has an antihypoxic and antiarrhythmic effect.
So which patients are prescribed Riboxin? Indications for use of this medication include diseases that require accelerated metabolic processes in the myocardium. After using this drug, it has a positive effect on all metabolic processes in the heart, and also contributes to an adequate relaxation of its muscles, especially during the diastole period.
The active substance of the drug is involved in glucose metabolism, improves blood circulation in the vessels (coronary), and also stimulates the recovery of ischemic tissues. We can not say that the use of the drug "Riboxin" helps to reduce hypoxia of internal organs.
Absorption and excretion of the drug
Presents the drug is metabolized in the liver, forming glucuronic acid. In the subsequent preparation is exposed to oxidation. Drug is excreted in small quantities with urine.
The drug "Riboxin": instructions, indications for use
According to the instructions attached to the drug, the drug Riboxin is prescribed for adults with the following deviations:
In what other cases, the drug "Riboxin" is prescribed (shots)? Indications for use of this tool include the following deviations:
- coronary atherosclerosis;
- open-angle glaucoma (but only under the condition of normal eye pressure);
- heart defects (acquired and congenital);
- dystrophic changes of the heart muscle, which were caused by heavy physical exertion or endocrine pathology;
- chronic and acute hepatitis;
- cirrhosis of the liver;
- damage to the liver of different origin and urokoproporfiriya.
It should be said that any form of the drug Riboxin should be used to treat the aforementioned diseases only after consulting a doctor.
Dosage of the drug and method of its use
The dose and method of use of the above means depend not only on the type of disease, but also on what form of the drug is used for treatment. Consider the instructions in more detail.
The drug "Riboxin" intravenously (the indications for use of this medication were presented above) should be administered slowlyjet or drip (45-55 drops per minute). Treatment with this agent begins with the introduction of 200 mg once a day. If the drug is well tolerated, the dose is increased to 400 mg (that is, to 20 ml of a 2% solution) twice a day. The duration of such therapy is 10-14 days.
It should also be noted that the jet injection of the drug is possible with acute disorders of the work and heart rhythm - in a single dosage equal to 200-400 mg.
How is Riboxin Bufus administered? Indications for use of this medication are similar to those for the means of "Riboxin", as this is just its trade name.
To protect the kidneys that were subjected to ischemia, the drug is administered intravenously in a single dose of 1.2 g (i.e., 60 ml of a 2% solution) 6-16 minutes before artery clamping (renal). After the blood circulation has been restored, another 0.8 g is administered to the patient (that is, 40 ml of a 2% solution).
If you need a drip of the drug in a vein, then a 2% solution is pre-diluted in 5% dextrose solution (i.e., glucose).
Capsules and pills "Riboxin" is prescribed by mouth before a direct meal.First, the patient must take 0.2 g of the drug four times a day, and then increase the dose to 9.4 g 6 times a day. The course of such therapy should last about 1-3 months.
Side effects after using the drug
There are few cases indicating that the drug Riboxin has side effects. So, some patients claim that after using the drug, they developed allergic reactions such as skin flushing, urticaria, and pruritus. In this case, the drug is better to cancel.
It should also be noted that with prolonged use of the drug in human blood, an increased concentration of uric acid can be observed, as well as aggravated gout.
When sharing the drug "Riboxin" with cardiac glycosides, this medicine can prevent the occurrence of any malfunction of the heart, as well as enhance the inotropic effect.
With simultaneous use with heparin in patients, an increase in the effect of the latter is observed and its duration increases markedly.
If the drug "Riboxin" should be used in the form of injections, it must be remembered that it is incompatible with alkaloids. When mixing these medications, insoluble compounds are formed.
Tablets and injections "Riboxin" can be taken without any fear in conjunction with such drugs as: "Nitroglycerin", "Furosemide", "Nifedipine", and "Spironolactone". This drug is incompatible with vitamin B6. When used simultaneously, both components are deactivated.
It must be said that the “Riboxin” solution (for injection) is extremely undesirable to mix with other drugs (except for the above-mentioned solvents) in one syringe or infusion system. If we ignore this advice, it can easily lead to undesirable chemical interaction of substances with each other.
Reviews of the drug and its price
In general, reviews of patients and doctors about the drug "Riboxin" are positive. However, sometimes there are isolated cases of allergic reactions in the form of itching, urticaria, and redness of the skin. Although such manifestations quickly disappear immediately after the cancellation of funds.
The main advantage of this drug compared to others is its price. As a rule, it varies in the range of 20-90 Russian rubles for 50 tablets and 10 ampoules, respectively. It should also be noted that the presented drug is well distributed in pharmacies. Therefore, if necessary, its acquisition will not be any work.